Job Description
Vertex Pharmaceuticals is searching for an experienced Associate Medical Director to serve as the Medical Lead forongoing clinical trials within the Hemoglobinopathy clinical development team. You will work as part of multidisciplinary cross-functional study teams on clinical trial strategy, design and execution, serving as the primary Medical Monitor responsible for monitoring the safety of subjects in multiple ongoing cell and gene therapy clinical trials in hemoglobinopathies. You will assist with the clinical development strategy, writing of study related materials, and act as a liaison between clinical development and other internal groups at Vertex and the VCGT. You may also participate in pipeline development activities in the Hemoglobinopathies program, depending on background and interest.
Key Duties and Responsibilities:
Serve on cross-functional Study Execution Teams (SETs) study teams for the assigned trials, working with other team members to achieve efficient, high-quality study execution, and data analysis
Participate and provide clinical and scientific subject matter expertise for the development of study related documents including study protocols, statistical analysis plans, informed consent forms (ICF), clinical research forms (CRF), investigator's brochures (IB), clinical study reports (CSR), and other key study-related documents in conjunction with other clinical development team members
Participate and provide input in the preparation of regulatory documents in support of global regulatory submissions, including safety reports, responses to regulatory authorities and ethics committees/IRBs, clinical study reports, and other documents as appropriate
Ability to work collaboratively in a fast-paced, team-based, matrixed environment and to function independently, as appropriate
Working knowledge of GCP, biostatistics, data management, clinical operations and clinical pharmacokinetics to support trial design and execution
Education and Experience:
Board certification/eligibilityin internal or pediatric medicine or another relevant medical field is highly desired; clinical development/experience in hematology and/or oncology, including hematopoietic stem cell transplant medicine, is a plus
8 years of basic or clinical research experience in an academic or industry setting, or the equivalent combination of education and experience, workingon cross-functional teams with experience involvingclinical trial design and execution,data analysis andscientific publication development
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Pay Range:
$198,300 - $297,400
Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.
Flex Designation:
Hybrid-Eligible Or On-Site Eligible
Flex Eligibility Status:
In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com
